Hades 2 Keepsake Tier List Best Picks And Rankings

Posted on 14 October 2026 | 50
News

Choosing the right keepsake in Hades 2 can completely transform the success of your run through the Underworld. These powerful items grant unique passive boons that help solve build weaknesses, improve survival, or boost damage output.

S-Tier Keepsakes for Every Run

Items in the top tier provide unparalleled versatility and strong stat benefits regardless of your current weapon choice. Odysseus's Knuckle Bones significantly reduces Guardian health while mitigating damage taken during boss fights. Additionally, Hecate's Silver Wheel gives a substantial boost to maximum Magick that remains active throughout your entire run.

A-Tier Picks for Build Utility

A-tier options provide excellent strategic utility when tailored to specific playstyles or middle-zone encounters. The Luckier Tooth from Schelemeus offers an essential second chance by restoring extra health upon defeat. Meanwhile, Nemesis's Evil Eye deals increased damage against the last enemy that killed you, making it ideal for tough encounters.

B-Tier Keepsakes for Situational Growth

B-tier keepsakes excel when swapped in during early or mid-game regions to shape your build progression. The Silken Sash from Arachne grants bonus armor after completing locations to protect your health pool. Furthermore, Olympian keepsakes allow players to target specific god blessings and improve boon rarity effectively.

How to Strategic Swap Keepsakes

To maximize your efficiency, equip resource or Magick-generating keepsakes in early regions before switching to defensive options. Replacing early items with boss-focused keepsakes like Knuckle Bones before final guardians ensures maximum combat advantage. Unlocking region transition display cases is crucial for mastering this swapping strategy.